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By 2025, innovations such as lab-on-a-chip technology, automation, and CRISPR-Cas9 gene editing are expected to enhance accessibility, success rates, and affordability of fertility care
technological innovations like automation and miniaturization of IVF laboratories through concepts like lab-on-a-chip technology are also set to revolutionize IVF
Advancements in assisted reproductive technologies (ART) are reshaping the future of fertility, with breakthroughs like in vitro fertilization (IVF) and in vitro gametogenesis (IVG) paving the way for significant progress. By 2025, innovations such as lab-on-a-chip technology, automation, and CRISPR-Cas9 gene editing are expected to enhance accessibility, success rates, and affordability of fertility care. Emerging trends also focus on personalized treatments, psychological support, and ethical considerations. With predictions that up to 10% of children in some regions may be conceived through IVF, the next decade promises transformative changes in how humans conceive and experience reproductive care.
Dr Muskaan Chhabra, IVF Specialist at Birla Fertility, Lajpat Nagar, New Delhi, says, “Steady advancements in assisted reproductive technologies (ART) and their implications for human reproduction depicts a promising future of fertility in 2025 and beyond. Driven by the evolving socio-demographic trends, there has been a significant increase in the demand for in vitro fertilization (IVF) and the fast-paced advancements in reproductive technology is further expected to reshape how humans conceive. Over the next decade, we are likely to see significant improvements in IVF success rates, personalized treatments, and ethical considerations surrounding fertility care. It is likely that in the near future, as many as 10% of all children will be conceived through IVF in many parts of the world.”
As we look ahead, futuristic approaches and technological innovations in the field hold the potential to improve IVF accessibility and success rates, while also reducing its cost and burden of care. “Medical advancements like the utilization of gonadotropins and portable ultrasound devices are expected to simplify monitoring and screening of patients. Integration of psychological screenings and counselling and coping interventions such as e-therapy will further enhance patient support,” shares Dr Chhabra.
Furthermore, technological innovations like automation and miniaturization of IVF laboratories through concepts like lab-on-a-chip technology are also set to revolutionize IVF. These advancements can significantly lower costs and improve outcomes by enabling the automation of virtually all the steps involved in a single system. Also, integration of microfluidics into the IVF laboratory will facilitate precise gamete manipulation, provide biomimetic environments for culture and facilitate microscale genetic and molecular bioassays.
Dr Chhabra adds, “The most revolutionary concept in modern reproductive science is that of in vitro gametogenesis (IVG). IVG comprises various approaches that have led to the creation of functional gametes in rodent models. Further innovations like in vitro gametogenesis (IVG) and CRISPR-Cas9 gene editing tools present new possibilities for creating functional gametes and modifying genetic material.”
Given the rapid scientific and technological evolution of reproductive genetics, it is imperative that both the public and regulatory bodies will soon be establishing a framework for the ethical evaluation of emerging technologies.
